Modulation of calcium-binding proteins expression and cisplatin chemosensitivity by calcium chelation in human breast cancer MCF-7 cells

Cisplatin (CDDP) is currently one of the most effective FDA-approved treatments for breast cancer.Previous studies have shown that CDDP-induced cell death in human breast cancer (MCF-7) cells is associated with disruption of calcium homeostasis.However, whether the sensitivity of breast cancer cells to cisplatin is associated with dysregulation of

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The application of GIS and its components in tourism

Since betty boop zombie the success of any tourism business is determined by tourism planning, development research and marketing, the first thing we review in this article is GIS application for tourism planning.Both tourism and IT increasingly provide strategic opportunities and powerful tools for economic growth, redistribution of wealth and dev

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Parasitic success and venom composition evolve upon specialization of parasitoid wasps to different host species

Female endoparasitoid wasps usually inject venom into hosts to suppress their immune response and ensure offspring development.However, the parasitoids ability to evolve towards increased success on a given host simultaneously with the evolution of the composition of its venom has never been demonstrated.Here, we designed an experimental evolution

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